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Vol.4 , No. 4, Publication Date: Aug. 23, 2017, Page: 38-43
 in patients attending Federal Medical Center, Katsina, Northwestern Nigeria. A total of 4237 urine samples from in-patients and out-patients with suspected cases of UTIs between 3<sup>rd</sup> January and 30<sup>th</sup> December, 2015 were collected and analysed using standard microbiological protocols. Antimicrobial susceptibility testing was done using Kirby-Bauer disc diffusion method. Breakpoints were compared using values provided by the Clinical and Laboratory Standards Institute (CLSI). Multidrug resistance (MDR) was defined by resistance to ≥ 3 antibiotics. The prevalence of UTIs recorded was 9.7% with more isolates recovered more from females than male counterparts (1.47:1). The uropathogens isolated were <i>Escherichia coli (E. coli) </i> (52.2%), <i>Staphylococcus aureus (S. aureus)</i> (32.8%), Klebsiella spp (1.9%), <i>Streptococcus spp</i> (4.5%), <i>Pseudomonas aeruginosa</i> (4.1%), <i>Proteus spp</i> (2.4%) and <i>Candida albicans</i> (2.2%). Most of the bacterial isolates were susceptible to fluoroquinolones and least susceptible to nalidixic acid, co-trimoxazole and tetracycline. The prevalence of Multidrug resistant bacteria was 47.8%. Findings from this study revealed that <i>E.coli </i>remains the most predominant etiology of UTIs. More so, the presence of multi-drug resistance bacteria was high. Hence, It’s recommended to treat urinary tract infections based on microbiology test results in order to prevent or minimize emergence and spread of multidrug resistant bugs.&picture=http://www.aascit.org/aascit/decorators/img/journal/906.jpg)
| [1] | Hammed Olusegun Ojokuku, Department of Medical Microbiology, Federal Medical Centre, Katsina, Nigeria. |
| [2] | Abubakar Suleiman Kankara, Department of Medical Microbiology, Federal Medical Centre, Katsina, Nigeria. |
| [3] | Idris Abdullahi Nasir, Department of Medical Laboratory Services, University of Abuja Teaching Hospital, Gwagwalada, FCT Abuja, Nigeria. |
| [4] | Abdullahi Olaleye Olawuyi, Department of Medical Microbiology, Federal Medical Centre, Katsina, Nigeria. |
| [5] | Morufat Bolanle Alao, Department of Medical Laboratory Science, College of Medical Sciences, University of Benin, Benin, Nigeria. |
Undoubtedly, urinary tract microbial colonization and infections are common causes of frequent hospital visits for medical care. Because of paucity of data in regards to the prevalence of uropathogens in Katsina state, this cross-sectional study was carried out to determine the profile and antimicrobial susceptibility pattern of urinary tract infections (UTIs) in patients attending Federal Medical Center, Katsina, Northwestern Nigeria. A total of 4237 urine samples from in-patients and out-patients with suspected cases of UTIs between 3rd January and 30th December, 2015 were collected and analysed using standard microbiological protocols. Antimicrobial susceptibility testing was done using Kirby-Bauer disc diffusion method. Breakpoints were compared using values provided by the Clinical and Laboratory Standards Institute (CLSI). Multidrug resistance (MDR) was defined by resistance to ≥ 3 antibiotics. The prevalence of UTIs recorded was 9.7% with more isolates recovered more from females than male counterparts (1.47:1). The uropathogens isolated were Escherichia coli (E. coli) (52.2%), Staphylococcus aureus (S. aureus) (32.8%), Klebsiella spp (1.9%), Streptococcus spp (4.5%), Pseudomonas aeruginosa (4.1%), Proteus spp (2.4%) and Candida albicans (2.2%). Most of the bacterial isolates were susceptible to fluoroquinolones and least susceptible to nalidixic acid, co-trimoxazole and tetracycline. The prevalence of Multidrug resistant bacteria was 47.8%. Findings from this study revealed that E.coli remains the most predominant etiology of UTIs. More so, the presence of multi-drug resistance bacteria was high. Hence, It’s recommended to treat urinary tract infections based on microbiology test results in order to prevent or minimize emergence and spread of multidrug resistant bugs.
Keywords
Antimicrobial Resistance, Uropathogens, Mutidrug Resistance
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