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Studying the Esterification of Phenylacetic Acid with some Hydroxylated Derivatives Using Eco-Friendly Medias

AASCIT Journal of Chemistry
Vol.3 , No. 5, Publication Date: Oct. 13, 2017, Page: 42-47

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Authors

[1]	Ghader Alhassan, Department of Chemistry, Faculty of Sciences, Al-Baath University, Homs, Syria.
[2]	Mohammad Keshe, Department of Chemistry, Faculty of Sciences, Al-Baath University, Homs, Syria.
[3]	Joumaa Merza, Chemistry of Natural Products, Department of Chemistry, Faculty of Science, Al-Baath University, Homs, Syria.

Abstract

In this research, the organic reaction of phenyl acetic acid and some Hydroxylated Derivatives in the absence of organic solvents to obtain phenyl acetic acid esters have been synthesized. The optimum reaction conditions were determined to produce phenyl acetic acid esters. The optimal condition (catalysts, temperature and solvents) to get a high selective compounds and high yields have been studied. When use of heterogeneous catalyst (Amberlyst-15) (10%mol), extra amount of reacted alcohol as a solvent and 110°C getting a required selectivity and high yield (about 80%) in comparison to the homogeneous catalysts (H₂SO₄, PTSA, CH₃SO₃H), in addition to the low selectivity of the final product. The reaction followed by using thin layer chromatography (T. L. C), the molecular structures have determinate by spectroscopy methods: FT-IR, ¹H-NMR, ¹³C-NMR.

Keywords

Esterification, Glycerol, Aromatic of Acitic Acid, Amberlyst-15, Spectroscopy Methods, Eco-Friendly Medias

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