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Vol.5 , No. 2, Publication Date: Apr. 9, 2019, Page: 42-44
. Statistical calculations were performed to determine the correlates of episodes of noncompliance leading to a relapse and re-hospitalization within one year of treatment. The data set included 87 symptoms relevant for studies of schizophrenia as well as numerous socio-demographic variables and data on the patient’s history of illness. Noncompliance was associated with symptoms of autism (r=.32, p=.001), widespread delusions (r=.25, p=.01), persistent persecutory delusions (r=.28, p=.004), and a relatively poor premorbid adjustment (r=.33, p=.001). The adjusted R<sup>2</sup> from a multiple regression suggested that the four variables accounted for 18% of variance in our noncompliance data.&picture=http://www.aascit.org/aascit/decorators/img/journal/929.jpg)
| [1] | Zack Zdenek Cernovsky, Department of Psychiatry, University of Western Ontario (Also Known as Western University), London, Canada. |
| [2] | Lamidi Kola Oyewumi, Department of Psychiatry, Department of Biomedical and Molecular Sciences, and Department of Psychology, Queen’s University, Kingston, Canada. |
| [3] | Harold Merskey, Department of Psychiatry, University of Western Ontario (Also Known as Western University), London, Canada. |
| [4] | Larry Craig Litman, Department of Psychiatry, University of Western Ontario (Also Known as Western University), London, Canada. |
This article presents analyses of de-identified archival data on the incidence of noncompliance with antipsychotic medication in a sample of 104 patients with schizophrenia (average age 38.2 years, SD=9.9; 41 men, 63 women). Statistical calculations were performed to determine the correlates of episodes of noncompliance leading to a relapse and re-hospitalization within one year of treatment. The data set included 87 symptoms relevant for studies of schizophrenia as well as numerous socio-demographic variables and data on the patient’s history of illness. Noncompliance was associated with symptoms of autism (r=.32, p=.001), widespread delusions (r=.25, p=.01), persistent persecutory delusions (r=.28, p=.004), and a relatively poor premorbid adjustment (r=.33, p=.001). The adjusted R2 from a multiple regression suggested that the four variables accounted for 18% of variance in our noncompliance data.
Keywords
Schizophrenia, Noncompliance, Autism, Delusions
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