ISSN: 2375-3900
American Journal of Pharmacy and Pharmacology  
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Anti-proliferative Active Flavonoids from the Methanol Extract of Indian Herb Artimisia reticulata
American Journal of Pharmacy and Pharmacology
Vol.5 , No. 4, Publication Date: Aug. 10, 2018, Page: 27-32
1759 Views Since August 10, 2018, 626 Downloads Since Aug. 10, 2018

Ajoy Kumar Bauri, Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India.


Peggy Jane Brodie, Department of Chemistry, Virginia Tech, Blacksburg, USA.


Sabine Foro, Institute of Materials Science, Darmstadt University of Technology, Darmstadt, Germany.


Nhu Quynh Nguyen Do, Accident and Emergency Department, Franco Vietnamese Hospital, Ho Chi Minh City, Vietnam.


Fractionations of defatted methanol extract of herb Artemisia reticulata have led to isolation of a series of flavonoids (1-5). Anti-proliferative assay of these flavonoids was carried out against A2780 human ovarian cancer cell lines to compare with the prescribed drug taxol. Amongst these five flavonoids, compound (4) exhibited maximum anti-proliferative activity against the above cell lines. The structure of the compounds was established by combination of the 1H and 13C NMR spectrum, EIMS analysis and was confirmed by X-ray diffraction study.


Flavonoids, Artemisia reticulata, Anti-proliferative Activity


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