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Vol.1 , No. 3, Publication Date: Aug. 20, 2014, Page: 23-27
 on Renal Functions among Persons Living with HIV and AIDS (PLWHA) in Sokoto, North Western Nigeria&description=HIV/AIDS is a global public health problem. As of 2012, approximately 35.3 million people were living with HIV/AIDS worldwide. The aim of this descriptive comparative was to determine the effect Highly Active Antiretroviral Therapy (HAART) of Stavudine, Lamivudine and Nevirapine on renal function of Persons Living with HIV and AIDS (PLWHA) accessing care at Usmanu Danfodiyo University Teaching Hospital Sokoto, North Western Nigeria. The level of total protein, albumin and creatinine were determined in 90 HIV- infected subjects aged 20-50 years. Thirty HIV-seronegative, age and gender- matched individuals were monitored as controls. Seventy of the HIV/AIDS infected patients were on HAART while 20 of the patients were yet to commence HAART. The level of the serum total protein and albumin observed among HIV infected subjects (on HAART and those not on HAART) and HIV negative controls were not significant (p > 0.05). Significant difference was observed in serum creatinine of HIV infected subjects on HAART and those not on HAART (p = 0.02). The results show that HAART of Stavudine, Lamivudine and Nevirapine improves renal creatinine clearance functions among the HIV positive clients but have no effect on levels of total protein and albumin.&picture=http://www.aascit.org/aascit/decorators/img/journal/922.jpg)
| [1] | Mainasara A. S., Faculty of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria. |
| [2] | Isah B. A., Department of Community Health, College of Health Sciences Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria. |
| [3] | Ahmed A. Y., Faculty of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria. |
| [4] | Erhabor O., Faculty of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria. |
HIV/AIDS is a global public health problem. As of 2012, approximately 35.3 million people were living with HIV/AIDS worldwide. The aim of this descriptive comparative was to determine the effect Highly Active Antiretroviral Therapy (HAART) of Stavudine, Lamivudine and Nevirapine on renal function of Persons Living with HIV and AIDS (PLWHA) accessing care at Usmanu Danfodiyo University Teaching Hospital Sokoto, North Western Nigeria. The level of total protein, albumin and creatinine were determined in 90 HIV- infected subjects aged 20-50 years. Thirty HIV-seronegative, age and gender- matched individuals were monitored as controls. Seventy of the HIV/AIDS infected patients were on HAART while 20 of the patients were yet to commence HAART. The level of the serum total protein and albumin observed among HIV infected subjects (on HAART and those not on HAART) and HIV negative controls were not significant (p > 0.05). Significant difference was observed in serum creatinine of HIV infected subjects on HAART and those not on HAART (p = 0.02). The results show that HAART of Stavudine, Lamivudine and Nevirapine improves renal creatinine clearance functions among the HIV positive clients but have no effect on levels of total protein and albumin.
Keywords
HIV, HAART, Renal Function, Liver Function
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