ISSN: 2375-3900
American Journal of Pharmacy and Pharmacology  
Manuscript Information
 
 
Medication Errors in Pediatric Hospitals
American Journal of Pharmacy and Pharmacology
Vol.1 , No. 4, Publication Date: Dec. 19, 2014, Page: 56-61
1282 Views Since December 19, 2014, 703 Downloads Since Apr. 12, 2015
 
 
Authors
 
[1]    

Darya Omed Nori, Department of Pharmacy, Sulaimani Pediatric Teaching Hospital, Kurdistan, Iraq.

[2]    

Tavga Ahmed Aziz, Department of Pharmacology and Toxicology, School of Pharmacy, Faculty of Medical Sciences, University of Sulaimani, Kurdistan, Iraq.

[3]    

Saad Abdulrahman Hussain, Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad, Baghdad, Iraq.

 
Abstract
 

Background: Drugs are a dualistic therapeutic tool, they are intended to cure, prevent or diagnose diseases, but improper use leads to patient morbidity or mortality. Aim: The present study was designed to evaluate medication errors (MEs) in Sulaimani Pediatric Hospital. Method: Prospective study was performed in Sulaimani Pediatric Teaching Hospital, Sulaimani City, Kurdistan Region, through which the physician medication orders for newly admitted patients from 6th February to 10th June 2013 were evaluated for MEs. A standardized questionnaire (especially adopted for the present study) was utilized to identify all expected types of MEs that appeared in the follow up sheets of randomly selected pediatric patients (n=100), admitted to the hospital due to different causes. Parents, usually mothers, answer some of the questions. 85% MEs were reported during prescribing practice. Results: They involved medications include bronchodilators 45%, anti-emetics 33%, antibiotics 32%, and analgesics and antipyretics 29%. The most frequently used antibiotics involved in the MEs were ceftriaxone 24%, ampicillin+cloxacillin 12% followed by cefotaxime and amikacin. The highest percentage of errors was 75% belonged to the use of teicoplanin followed by amikacin 60%. Conclusion: The percentages of MEs in Sulaimani Pediatric Hospital are very high, and there is irrational use of antibiotics. Most of MEs are avoidable utilizing the roles and activities of clinical pharmacists to provide maximum health care services.


Keywords
 

Pediatrics, Medication Errors, Antibiotics, Prescribing Practice


Reference
 
[01]    

Kohn L, Corrigan J, Donaldson M, (Eds.), To Err Is Human: Building a Safer Health System. Committee on Quality of Health Care in America, Institute of Medicine, Washington, DC, National Academy Press, 1999.

[02]    

Koren G, Barzilay Z, Greenwald M. Ten-fold errors in administration of drug doses: a neglected iatrogenic disease in pediatrics. Pediatrics 1986; 77:848-849.

[03]    

Koren G, Haslam RH. Pediatric medication errors: predicting and preventing ten-fold disasters. Journal of Clinical Pharmacology 1994; 34:1043-1045.

[04]    

Rowe C, Koren T, Koren G. Errors by pediatric residents in calculating drug doses. Archive of Disease in Children 1998; 79:56-58.

[05]    

Glover ML, Sussmane JB. Assessing pediatrics residents’ mathematical skills for prescribing medication: a need for improved training. Academic Medicine 2002; 77:1007-1010.

[06]    

Gladstone J. Drug administration errors: a study into the factors underlying the occurrence and reporting of drug errors in a district general hospital. Journal of Advanced Nursing 1995; 22:628-637.

[07]    

Yeung YW, Tuleu CL, Wong ICK. National study of extemporaneous preparations in English paediatric hospital pharmacies. Pediatric and Perinatal Drug Therapy 2004; 6:75-80.

[08]    

Chappell K, Newman C. Potential tenfold drug overdoses on a neonatal unit. Archive of Diseases in Children, Fetal and Neonatal Education 2003; 89:F483-484.

[09]    

Tan E, Cranswick NE, Rayner CR, et al. Dosing information for paediatric patients: are they really ‘‘therapeutic orphans’’? Medical Journal Australia 2003; 179:195-198.

[10]    

Wong ICK, Basra N, Yeung V, et al. Supply problems of unlicensed and off-label medicines after discharge. Archive of Disease in Children 2006; 91:686-688.

[11]    

Lesar TS, Mitchell A, Sommo P. Medication safety in critically ill children. Clinical Pediatrics and Emergency Medicine 2006; 7:215-225.

[12]    

Korin G. Trend of medication errors in hospitalized children. Journal of Clinical Pharmacology 2002; 42:707-710.

[13]    

Bates DW, Cullen DJ, Laird N, et al. Incidence of adverse drug events and potential adverse drug events implications of prevention. Journal of American Medical Association 1995; 274:29-34.

[14]    

Leape LL, Bates DW, Cullen DJ, et al. Systemic analysis of adverse drug events. Journal of American Medical Association 1995; 274:35-43.

[15]    

Folli HL, Poole RL, Benitz WE, Russo JC. Medication error prevention by clinical pharmacists in two children's hospitals. Pediatrics 1987; 79:718-722.

[16]    

Montazeri M, Cook DJ. Impact of clinical pharmacist in a multi-disciplinary intensive care unit. Critical Care Medicine 1994; 22:1044-1048.

[17]    

Kaushal R, Bates DW, Landrigan C, et al. Medication errors and adverse drug events in pediatric inpatients. Journal of American Medical Association 2001; 285:2114-2120.

[18]    

Fortescue EB, Kaushal R, Landrigan CP, et al. Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatients. Pediatrics 2003; 111:722-729.

[19]    

Stebbing C, Wong ICK, Kausha R, et al. The role of communication in pediatric drug safety. Archive of Diseases in Children 2007; 92:440-445.

[20]    

Wong ICK, Wong LYL, Cranswick NE. Minimizing medication errors in children. Archive of Diseases in Children 2009; 94:161-164.

[21]    

Kaushal R, Jaggi T, Walsh K, Fortescue EB, Bates DW. Pediatric medication errors. Ambulatory Pediatrics 2004; 4(1):73-81.

[22]    

Straand J, Rokstad K, Heggedal U. Drug prescribing for children in general practice: A report from the More and Romsdal prescription study. Acta Pediatrica 1998; 87:218-224.

[23]    

Sanz EJ, Bergman U, Dahlstorm M. Pediatric drug prescribing. European Journal of Clinical Pharmacology 1989; 37:65-68.

[24]    

Ghai OP, Paul VK. Rational drug therapy in pediatric practice. Indian Pediatrics 1988; 25:1095-1109.

[25]    

Neubert A, et al. Databases for pediatric medicine research in Europe: assessment and critical appraisal. Pharmacoepidemiology and Drug Safety 2008; 17:1155-1167.

[26]    

Dimri S, Tiwari P, Basu S, Parmar VR. Drug use pattern in children at a teaching hospital. Indian Pediatrics 2009; 46(2):165-167.

[27]    

Khaled A, Sami M, Majed I, Mostafa A. Antibiotic prescribing in a pediatric emergency setting in central Saudi Arabia. Saudi Medical Journal 2011; 32(2):197-198.

[28]    

Yewale VN, Dharmapalan D. Promoting appropriate use of drugs in children. International Journal of Pediatrics 2012; 10:9065-9070.

[29]    

Al-Jeraisy M, Alanazi MQ, Abolfotouh M. Medication prescribing errors in a pediatric inpatient tertiary care setting in Saudi Arabia. BMC Research Notes 2011; 4:294.





 
  Join Us
 
  Join as Reviewer
 
  Join Editorial Board
 
share:
 
 
Submission
 
 
Membership