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American Journal of Microbiology and Biotechnology

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Haematological Parameters of Individuals Infected with Plasmodium falciparum in Parts of Kaduna Metropolis, Kaduna State, Nigeria

American Journal of Microbiology and Biotechnology
Vol.5 , No. 3, Publication Date: Sep. 20, 2018, Page: 37-43

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Authors

[1]	Karderam Bukar Dikwa, Department of Biological Sciences, Nigerian Defence Academy, Kaduna, Nigeria.
[2]	Umar Abdullahi Yahaya, Department of Biological Sciences, Nigerian Defence Academy, Kaduna, Nigeria.
[3]	Dominic Bawa Maikaje, Department of Microbiology, Kaduna State University, Kaduna, Nigeria.
[4]	Ahmad Babangida Suleiman, Department of Microbiology, Ahmadu Bello University, Zaria. Nigeria.

Abstract

Malaria remained a major public health problem in Nigeria, Plasmodium falciparum account for most malaria cases, changes in haematological parameters are main features of P. falciparum infection. The aim of this study is to assess changes in haematological parameters of P. falciparum infected symptomatic and asymptomatic individuals. Five hundred blood samples from each category were collected. Parasites detection and parasitaemia level determination were performed on thick blood films, parasites were identified on thin film. Complete Blood Counts (CBCs) of all blood samples were performed using automated blood analyser (Model KX-21N. Sysmex, Japan). Results shows significantly lower mean (±SD) values of neutrophils, RBC, Hb, PCV, MCHC, MCH and MCV in symptomatic individuals compare to asymptomatic individuals (P<0.05). Packed Cell Volume and MCH were significantly lower (P<0.05) in symptomatic individuals with high level of parasitaemia. Significant increase in lymphocytes and monocytes was observed in symptomatic and asymptomatic individuals with high parasitaemia, Platelets level was significantly lower in asymptomatic individuals. Reduced PCV values recorded are features of anaemia, reduced red cell indices are features of iron deficiency anaemia. Significant increase in lymphocytes observed in this study may be attributed to antimalarial drugs intake by symptomatic individuals.

Keywords

Haematological Parameters, P. falciparum Infection, Symptomatic, Asymptomatic, Individuals

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