






Vol.3 , No. 2, Publication Date: Jun. 13, 2017, Page: 15-19
[1] | marenezor Edobor Peter Kenneth, Medical Microbiology Unit, Department of Microbiology, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria. |
[2] | Brown Samuel Tamunoiyowuna Cockeye, Medical Parasitology Unit, Department of Microbiology, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria. |
[3] | Babatope Isaac Olaniyi, Department of Medical Laboratory Science, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria. |
Urinary schistosomiasis and bacteriuria was investigated in Enwan community in order to determine the various bacteria associated with the infection and there antibiogram. A total of 300 Positive individuals for Schistosoma haematobium, comprising of 193 (64.3%) males and 107 (35.7%) females had their urine samples collected, examined and cultured using standard bacteriological techniques. The bacteria isolated include: Escherichia coli 30 (30.6%), Klebsiella aerogenes 22 (22.5%), Pseudomonas aeruginosa 12 (12.2%), Proteus rettgeri 24 (24.5%) and Staphylococcus aureus 10 (10.2%) in the decreasing order of isolate. The antimicrobial sxusceptibility pattern of these bacteria revealed varying susceptibilies by all isolates to Gentamycin and Erythromycin but was resistant to Amoxicillin. Klebsiella aerogenes was sensitive to all except Septrin, Ampiclox and Amoxicillin. Escherichia coli were sensitive to all and resistant to Sephrin, Pefloxacin, Ampiclox, Amoxicillin and Rocephin. Pseudomonas aeruginosa was resistant to Sephrin, Ampiclox, zinnacef and Amoxicillin but sensitive to other antibiotic used. Proteus rettgeri was resistant to Streptomycin, Ampiclox, Amoxicillin, Rocephin and Ceprofloxacin and sensitive to others. Staphylococcus aureus was sensitive to all the antimicrobial agents used but were resistant to Sephrin, Pefloxacin, Amoxicillin and Rocephin. This study clearly illustrates that bacteriuria is a major difficulty encountered in the management of urinary schistosomiasis. Therefore, there is also need to incorporate antibacterial therapy to the integrated morbidity control approach of diagnosis, drugs treatment, snail control in mass schistosomicidal treatment programmes along with other public health interventions such as access to safe water, improved sanitation, health education, health communication and appropriate case management.
Keywords
Schistosomiasis, Bacteriuria, Antimicrobial, Urine, Enwan, Edo State
Reference
[01] | Brooker, S. Vander, W. M. J., Darlas, S. J., Looman, C. W and Nagel, K. N. J (2003) Quantification of clinical morbidity associated with schistosome infection in sub-saharan Africa. Actic Tropical 86: 125-139. |
[02] | World Health Organization (2001). The control of schistosomiasis: second report of the WHO expert committee: World. Health Organization Technical Report Series 750: 1. |
[03] | Imarenezor, E. P. K, Nmorsi, O. P. G, Eghafona, N. O, Ohenhen, R. E, Ekozien, M. I. (2013). Prevalence of urinary schistosomiasis in Ewan a rural community in Akoko – Edo local government, Edo State, Nigeria. International Journal of pure and applied sciences. 2 (2) 189–192. |
[04] | Nmorsi, O. P. G. (1996). Schistosomatidae: In principles of parasitology. Pon Publishers, Nigeria. Pp 100-110. |
[05] | Van, L. (2000). Immunodiagnosis of schistosomiasis by determination of circulating antigens CAA and CCA in particular individuals with recent or light infection. Acta. Tropical Special Issues 74: 69-80. |
[06] | Buzdech, U. (1973). The incidence of schistosoma haematobium, S. mansoni in urban Nigeria. Zenti. Bakti. org. Ser. A. 224(2) 264-269. |
[07] | Anderson, R. M. (1987) Determinnats of infection in human schistosomiasis. Ballier’s Clinical Tropical Medicine Communicable Diseases. 2: 279-209. |
[08] | Nmorsi, O. P. G., Egwunyenga, O. A and Bojomo, D. O. (2001). A survey of urinary schistosomiasis and trichomoniasis in rural community in Edo State, Nigeria. Acta. Medical et. Biologica. 49(1): 25-29. |
[09] | Adewunmi, C. O., Gebremedin G., Becker W., Olurunmola F. O. and Dorfler O. (1993) Schistosmiasis and intestinal parasites in rural villages in south west in Nigeria: An indication for expanded and integrated control programme in Nigeria. Tropical Medicine Parasitology 44(3): 177-180. |
[10] | Audu, J. O (1980) Schistosmiasis, it prevalence in Kaduna polytechnic, Nigeria. Tropical Doctors 18: 46-47. |
[11] | Woolhouse, M. E. J., Taylor, P., Matantiire, D and Chandiwana, S. K. (1991). Acquired immunity and epidemiology of Schistosoma haematobium. Nature 351: 757-759. |
[12] | Arinola, O. G and Salimonu, L. S (1995) Prevalence and severity of urinary schistosomiasis in Ibadan, Nigeria. East Africa Medical Journal 74(5): 64-67. |
[13] | Chitsulo, L., Engels, D., Montresor, A. and Savioli, L. (2000). The global status of schistosmiasis and its control. Acta Troical. 77: 41-57. |
[14] | Imarenezor, E. P. K, Brown, S. T. C, Yakubu, O. E and Abhadionmhen, O. A (2016). Interleukin (IL)- 10 Profile among Nigerians with Schisotoma haematobium infection. FUW Trends in Science and Technology Journal. 1(1): 24–25. |
[15] | Medhatt, A., Shehata, M., Buccik, M. S., Dief, A. D., Badary, S. G., Nafeh, D and King, C. K. (2004). Increased interleukin 4 and interleukin -5- production in response to Schistosomia haematobium Adult worm antigen correlates with lack of oral infection after treatment. Journal of infecious Diseases 198: 512-519. |
[16] | Celso, L. G., Carla, B. M., Varalucia, D. S and Marcio, G. (1998). Simplified technique for detection of significant bacteriuria by microscopic examination of urine. Journal of clinical Microbiology. 3: 830-823. |
[17] | Lengeler, C., Desavigny, D., Mshinds, H., Mayombana, C., Tayan, S., Hatz, C and Degremont, A. (1991). Community based questionnaires and health statistics as tools for the cost efficient identification of communities at risk of urinary schistosomiasis. International Journal epidemiology 20: 769-807. |
[18] | Jordan, P. (1997). Schistosomiasis: research and control. America journal Tropical Medicine Hygiene 26(5): 877-886. |
[19] | Mutapi, F., Burchmore, R., Foucher, A., Harcus, Y., Maizeles, R. (2005). Praziquantel treatment of people exposed to schistosoma haematobium enhances serological recognition of defined parasite antigens. Journal of infectious Disease 192: 1108-1118. |
[20] | Mostafa, M. H., Sheweita, S. A and Connor, P. J. (1999). Relationship between schistosomiasis and bladder cancer. Clinical Microbiology Review 12(11): 97-111. |
[21] | Abath, F. G., Morais, C. N., Montenegro C. E., Wynn Y. A. and Montenegro S. M. (2006) Immunopathogenic mechanisms in schistosomiasis: what can be learnt from human studies? Trends. Parasitology 22: 85-91. |
[22] | Bauer, A. W., Kirby, W. M., Sherris, J. C and Turk M (1996) Antibiotic susceptibility testing by a standardized single disc method. America Journal clinical Pathology. 45: 493-496. |
[23] | Doenhoff, M. J., Cioli, D and Utzinger, J. (2008). Praziquantel mechanisms of action, resistance and new derivatives for schistosomiasis. Current Opinion Infectious Diseases. 21: 659-667. |
[24] | Andrews, J. M. (2001) BSAC standardized disc susceptibility testing method. Journal antimicrobial Chemothrapy 48: 43-47. |