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Vol.1 , No. 1, Publication Date: Mar. 19, 2015, Page: 6-12
 administered ghrelin (3 nmol/200 µl saline for each bird) on food intake and energy expenditure as measured in respiratory chambers by indirect calorimetry for 12 h in adult male Japanese quail. Plasma glucose, triglycerides, free fatty acids, total protein and T3 were measured in a separate experiment until 2 hour after peripheral administration. Food intake was measured until 12 h after ghrelin administration and showed decrease at all time points measured. The respiratory quotient in ghrelin-administered quail was reduced until 12 h after administration whereas plasma glucose and triglycerides concentrations were not changed. Free fatty acids and total protein levels also remained unchanged. Ghrelin did not influence heat production and this was supported by the absence of changes in plasma T3 levels when compared to the control values. In conclusion, peripheral ghrelin reduces food intake and therefore has a role in energy homeostasis in avian species.&picture=http://www.aascit.org/aascit/decorators/img/journal/890.jpg)
| [1] | Shousha S., Department of Physiology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Egypt. |
| [2] | Kirat D., Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt. |
| [3] | Naso T., Department of Basic Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan. |
Ghrelin is a peptide found in the mucosal layer of the rat stomach that exhibits growth hormone–releasing and appetite-stimulating activities. Ghrelin administration, either centrally or peripherally strongly stimulates feeding in human and rodents. Since the discovery of ghrelin in chicken in 2002, information on its structure, distribution, function, and receptors has been accumulated, mainly in poultry. In contrast to mammals and rodents, centrally injected ghrelin inhibits food intake in neonatal chickens, Japanese quail. No information is available about the mechanism and its relationship with energy homeostasis in Japanese quail. Since ghrelin is predominantly produced in the proventriculus in birds, we investigated the effect of peripherally (intraperitoneal) administered ghrelin (3 nmol/200 µl saline for each bird) on food intake and energy expenditure as measured in respiratory chambers by indirect calorimetry for 12 h in adult male Japanese quail. Plasma glucose, triglycerides, free fatty acids, total protein and T3 were measured in a separate experiment until 2 hour after peripheral administration. Food intake was measured until 12 h after ghrelin administration and showed decrease at all time points measured. The respiratory quotient in ghrelin-administered quail was reduced until 12 h after administration whereas plasma glucose and triglycerides concentrations were not changed. Free fatty acids and total protein levels also remained unchanged. Ghrelin did not influence heat production and this was supported by the absence of changes in plasma T3 levels when compared to the control values. In conclusion, peripheral ghrelin reduces food intake and therefore has a role in energy homeostasis in avian species.
Keywords
Japanese Quail, Ghrelin, Food Intake, Energy Homeostasis
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